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The distribution of septal projections to the hippocampus of the rat
Author(s) -
Mosko Sarah,
Lynch Gary,
Cotman Carl W.
Publication year - 1973
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.901520204
Subject(s) - hippocampal formation , biology , acetylcholinesterase , dentate gyrus , hippocampus , neuroscience , anatomy , septal nuclei , enzyme , biochemistry
Terminal degeneration following lesions of the medial septal nucleus or of the contralateral hippocampus was mapped and compared with the distribution of acetylcholinesterase in the hippocampal formation of the rat. Previously unreported septal projections were found in the supragranular region of the dentate gyrus, an area which is also the locus of a dense band of acetylcholinesterase. This correspondence provides further support for the hypothesis that the enzyme is located in the septal efferents. These findings are combined with those of earlier workers in a hypothetical model of septo‐hippocampal relationships.