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An experimental analysis of the determination of cell patterns in the spinal cord of the chick embryo
Author(s) -
Narayanan C. H.
Publication year - 1970
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.901390203
Subject(s) - spinal cord , neural tube , biology , embryo , anatomy , somite , cord , notochord , vertebral column , transplantation , basal plate (neural tube) , embryogenesis , neuroscience , microbiology and biotechnology , fetus , medicine , pregnancy , genetics , geometry , mathematics , placenta
The effects of rotation of the brachial region of the spinal cord about its longitudinal axis between stages 12 to 15 were studied in a series of 30 chick embryos by transplanting that portion of the neural tube opposite somite levels 16 to 20 from a donor embryo to a host embryo at the same stage of development. Despite the altered topographical relationship between the transplanted neural tube and the adjacent mesodermal somites, the cytological characteristics of the cells and the organization of the major cell groups derived from the alar and basal halves of the cord remained unaffected. In the more successful experiments, well‐developed lateral motor columns and ventral roots and dorsal roots and spinal ganglia could be identified in the usual morphological relationships even though the graft piece of spinal cord was clearly inverted compared to the remaining part of the spinal cord of the host embryo. A limited number of cell counts of the lateral motor column in some of these cases showed no significant difference in cell number, nor was there an appreciable change in the general morphology of the cell groups in the transplanted cord compared to the lateral motor columns of control embryos at similar developmental stages.