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Nigrofugal connections in the primate brain
Author(s) -
Mettler Fred A.
Publication year - 1970
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.901380304
Subject(s) - globus pallidus , substantia nigra , putamen , biology , neuroscience , anatomy , caudate nucleus , primate , thalamus , projection (relational algebra) , pars reticulata , basal ganglia , central nervous system , dopamine , dopaminergic , algorithm , computer science
The great mass of large cells which make up the compact part of the substantia nigra send their stout primary axons to the ipsilateral globus pallidus. A much smaller‐ipsilateral striatal projection can also be easily substantiated. This comes chiefly from cells in the reticulata but not exclusively so. In general, the lateral reticulata projects to the putamen and the medial to the caudate. If the synapses in the ventrolateral part of the thalamus, which have been described to degenerate to degenerate after lesions in the nigra, are established by nigrofugal, rather than by other fiber systems, they would seem to be the endings of collaterals given off en route to the lentiform nucleus, rather than primary projection elements. If any fibers from the nigra cross the midline, or descend, they must be very few.