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Perinatal changes in epidermal innervation in rat and mouse
Author(s) -
Fitzgerald M. J. T.
Publication year - 1966
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.901260103
Subject(s) - biology , epidermis (zoology) , dermis , free nerve ending , anatomy , immunohistochemistry , neuroscience , immunology
The development of cutaneous innervation in the rat and the rat and the mouse has been studied by silver techniques. In particular, the innervation patterns of adult and of perinatal skin have been compared. From the second parental day until the sixth postnatal day, the relatively thick epidermis is freely penetrated by nerve fibers; thereafter, the nerve endings appear to be confined to the dermis. The intra‐epidermal axons are directed obliquely, with a rough (and not exact) correspondence to the plane of future emergence of the hair shafts. The appearance of a transitory development of intra‐epidermal nerves elsewhere.