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Medial temporal cortices in ex vivo magnetic resonance imaging
Author(s) -
Augustinack Jean C.,
Kouwe André J.W.,
Fischl Bruce
Publication year - 2013
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.23432
Subject(s) - ex vivo , magnetic resonance imaging , entorhinal cortex , hippocampal formation , neuroscience , temporal lobe , in vivo , biology , anatomy , medicine , radiology , microbiology and biotechnology , epilepsy
This review focuses on the ex vivo magnetic resonance imaging (MRI) modeling of medial temporal cortices and associated structures, the entorhinal verrucae and the perforant pathway. Typical in vivo MRI has limited resolution due to constraints on scan times and does not show laminae in the medial temporal lobe. Recent studies using ex vivo MRI have demonstrated lamina in the entorhinal, perirhinal, and hippocampal cortices. These studies have enabled probabilistic brain mapping that is based on the ex vivo MRI contrast, validated to histology, and subsequently mapped onto an in vivo spherically warped surface model. Probabilistic maps are applicable to other in vivo studies. J. Comp. Neurol. 521:4177–4188, 2013. © 2013 Wiley Periodicals, Inc.