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Two populations of corticothalamic and interareal corticocortical cells in the subgranular layers of the mouse primary sensory cortices
Author(s) -
Petrof Iraklis,
Viaene Angela N.,
Sherman S. Murray
Publication year - 2012
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.23006
Subject(s) - biology , neuroscience , sensory system , subgranular zone , anatomy , microbiology and biotechnology , progenitor cell , stem cell , subventricular zone
Abstract The subgranular layers (layers 5 and 6) of primary sensory cortex provide corticofugal output to thalamus and they also project to the appropriate secondary sensory cortices. Here we injected two combinations of different color retrograde fluorescent markers in the thalamic and cortical targets of these layers from the three primary sensory cortices (somatosensory, auditory, and visual) in mice to examine the degree of overlap between corticothalamic and interareal corticocortical cells in the subgranular layers. We found that, for all three primary sensory cortices, double‐labeled cells were extremely rare, indicating that corticothalamic and interareal corticocortical cells in the subgranular layers represent largely independent populations. J. Comp. Neurol. 520:1678–1686, 2012. © 2011 Wiley Periodicals, Inc.