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Stereological study of postnatal development in the mouse utricular macula
Author(s) -
Kirkegaard Mette,
Nyengaard Jens R.
Publication year - 2005
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.20736
Subject(s) - stereology , biology , anatomy , period (music) , endocrinology , acoustics , physics
This study describes the morphometric changes taking place in the utricular macula of mice with ages in geometric progression from 1 to 512 days after birth. By using design‐based stereological methods, the total volume and surface area of the sensory epithelium as well the total number of the hair cells and supporting cells were estimated. Finally, the numerical density, volume density, and mean volume of the individual cell types were determined. The major changes were found in the number of the individual cell types during the first couple of weeks, and a mature composition of cell types was not attained until 16 days after birth. There was no change in the total number of cells and no decline in the number of hair cells within the time period studied. J. Comp. Neurol. 492:132–144, 2005. © 2005 Wiley‐Liss, Inc.