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High apoptotic index in urine cytology is associated with high‐grade urothelial carcinoma
Author(s) -
Rosenthal Dorothy L.
Publication year - 2016
Publication title -
cancer cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.29
H-Index - 57
eISSN - 1934-6638
pISSN - 1934-662X
DOI - 10.1002/cncy.21723
Subject(s) - medicine , urothelial carcinoma , cytology , urine cytology , urine , urinary system , urothelial cancer , pathology , urology , cancer , bladder cancer , cystoscopy
In this issue, Yang and colleagues report that, using a high apoptotic index as a feature, the 2 categories “high‐grade urine cytology” (HGUC) and “atypical urothelial cells, cannot exclude HGUC,” yield almost equal numbers of samples that, when combined, result in a tissue diagnosis of HGUC 79% of the time. The authors conclude that adding a high apoptotic index to the traditional cytologic features of urothelial carcinoma can improve the sensitivity of urinary cytology for detecting HGUC. See also pages 546‐51.