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Detection and characterization of circulating tumor cells in lung cancer: Why and how?
Author(s) -
Hofman Véronique J.,
Ilie Marius,
Hofman Paul M.
Publication year - 2016
Publication title -
cancer cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.29
H-Index - 57
eISSN - 1934-6638
pISSN - 1934-662X
DOI - 10.1002/cncy.21651
Subject(s) - medicine , lung cancer , cancer , stage (stratigraphy) , disease , intensive care medicine , oncology , liquid biopsy , pathology , paleontology , biology
Lung cancer is the leading cause of cancer death worldwide. It has a poor prognosis, with a survival rate of 15% after 5 years for all pTNM stages of disease. The poor prognosis is mainly due to the fact that diagnosis is made at a late inoperable stage. New approaches aimed at improving the quality and length of life among these patients are urgently needed. These advances are expected to come from noninvasive, predictive, and personalized new tests, recently referred to as “liquid biopsies,” which are used for diagnostic, prognostic, and theragnostic purposes.