Premium
Abrogation of survival disparity between Black and White individuals after the USPSTF′s 2012 prostate‐specific antigen–based prostate cancer screening recommendation
Author(s) -
Kim Isaac E.,
Jang Thomas L.,
Kim Sinae,
Modi Parth K.,
Singer Eric A.,
Elsamra Sammy E.,
Kim Isaac Yi
Publication year - 2020
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.33179
Subject(s) - medicine , prostate cancer , prostate cancer screening , prostate specific antigen , epidemiology , task force , white (mutation) , demography , gynecology , cancer , gene , biochemistry , chemistry , public administration , sociology , political science
Background In May 2012, the US Preventive Services Task Force (USPSTF) recommended against prostate‐specific antigen (PSA)–based screening for prostate cancer (PCa), assigning it a grade D. This decision then was modified in 2018 to a grade C for men aged 55 to 69 years. The authors hypothesized that changes in screening practices would reduce survival outcomes for both Black and White men but maintain racial discrepancies in outcomes. Methods Using the Surveillance, Epidemiology, and End Results database, the authors examined PCa‐specific survival based on race and year of diagnosis. The period between January 2010 and December 2012 was categorized as the pre‐USPSTF era, whereas the period between January 2014 and December 2016 was classified as the post‐USPSTF era. The year 2013 was considered the transition year and was excluded from the analysis. Results A total of 49,388 men were identified in the pre‐USPSTF era who were diagnosed with PCa, approximately 83.7% of whom were White and 16.3% of whom were Black. In the post‐USPSTF era, a total of 41,829 men were diagnosed with PCa, approximately 82.7% of whom were White and 17.3% of whom were Black. When compared with the pre‐USPSTF era, men diagnosed in the post‐USPSTF era were found to have more adverse clinical features. In the pre‐USPSTF era, White men were less likely to die of PCa than Black men. This survival disparity between White and Black men was no longer observed in the post‐USPSTF era. Conclusions In men diagnosed with PCa between 2014 and 2016, a survival disparity between White and Black men was not observed due to a decrease in survival among White men while the survival of Black men remained steady.