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Complexities in estimating the true risk of hereditary leiomyomatosis and renal cell carcinoma and the development of kidney cancer
Author(s) -
Ball Mark W.,
Ricketts Christopher J.
Publication year - 2020
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.32915
Subject(s) - medicine , penetrance , leiomyomatosis , incidence (geometry) , cancer , renal cell carcinoma , kidney cancer , kidney , oncology , pathology , phenotype , genetics , biology , physics , leiomyoma , gene , optics
Currently, the incidence of hereditary leiomyomatosis and renal cell cancer (HLRCC), as well as the penetrance of kidney cancer among patients with HLRCC, is unknown. Large‐scale genomic databases may be unable to accurately estimate the incidence of HLRCC.