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Renal cell carcinoma with isolated lymph node metastases should be reclassified as stage IV
Author(s) -
Shapiro Daniel D.,
Abel E. Jason
Publication year - 2020
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.32913
Subject(s) - medicine , renal cell carcinoma , lymph node , stage (stratigraphy) , oncology , carcinoma , cancer , population , paleontology , environmental health , biology
On the basis of institutional and population‐based data, it has become clear that the risk of progression is distinctly different for lymph node–positive (LN+)/M0 renal cell carcinoma in comparison with locally advanced, nonmetastatic renal cell carcinoma. It is critical that the American Joint Committee on Cancer staging system recognize the increased risk with LN+/M0 tumors and consider reclassification of LN+/M0 as stage IV.