Premium
Rectal cancer survival in the United States by race and stage, 2001 to 2009: Findings from the CONCORD‐2 study
Author(s) -
Joseph Djenaba A.,
Johnson Chris J.,
White Arica,
Wu Manxia,
Coleman Michel P.
Publication year - 2017
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.30882
Subject(s) - medicine , demography , relative survival , population , stage (stratigraphy) , survival analysis , race (biology) , epidemiology , cancer , survival rate , colorectal cancer , negroid , gerontology , cancer registry , surgery , sociology , biology , botany , environmental health , paleontology
BACKGROUND In the first CONCORD study, 5‐year survival for patients with diagnosed with rectal cancer between 1990 and 1994 was <60%, with large racial disparities noted in the majority of participating states. We have updated these findings to 2009 by examining population‐based survival by stage of disease at the time of diagnosis, race, and calendar period. METHODS Data from the CONCORD‐2 study were used to compare survival among individuals aged 15 to 99 years who were diagnosed in 37 states encompassing up to 80% of the US population. We estimated net survival up to 5 years after diagnosis correcting for background mortality with state‐specific and race‐specific life table. Survival estimates were age‐standardized with the International Cancer Survival Standard weights. We present survival estimates by race (all, black, and white) for 2001 through 2003 and 2004 through 2009 to account for changes in collecting the data for Surveillance, Epidemiology, and End Results Summary Stage 2000. RESULTS There was a small increase in 1‐year, 3‐year, and 5‐year net survival between 2001‐2003 (84.6%, 70.7%, and 63.2%, respectively), and 2004‐2009 (85.1%, 71.5%, and 64.1%, respectively). Black individuals were found to have lower 1‐year, 3‐year, and 5‐year survival than white individuals in both periods; the absolute difference in survival between black and white individuals declined only for 5‐year survival. Black patients had lower 5‐year survival than whites at each stage at the time of diagnosis in both time periods. CONCLUSIONS There was little improvement noted in net survival for patients with rectal cancer, with persistent disparities noted between black and white individuals. Additional investigation is needed to identify and implement effective interventions to ensure the consistent and equitable use of high‐quality screening, diagnosis, and treatment to improve survival for patients with rectal cancer. Cancer 2017;123:5037‐58 . Published 2017. This article is a U.S. Government work and is in the public domain in the USA.