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Cervical cancer: A global health crisis
Author(s) -
Small William,
Bacon Monica A.,
Bajaj Amishi,
Chuang Linus T.,
Fisher Brandon J.,
Harkenrider Matthew M.,
Jhingran Anuja,
Kitchener Henry C.,
Mileshkin Linda R.,
Viswanathan Akila N.,
Gaffney David K.
Publication year - 2017
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.30667
Subject(s) - medicine , cervical cancer , radiation therapy , cancer , brachytherapy , chemoradiotherapy , regimen , malignancy , cervix , disease , intensive care medicine , gynecology , oncology , surgery
Cervical cancer is the fourth most common malignancy diagnosed in women worldwide. Nearly all cases of cervical cancer result from infection with the human papillomavirus, and the prevention of cervical cancer includes screening and vaccination. Primary treatment options for patients with cervical cancer may include surgery or a concurrent chemoradiotherapy regimen consisting of cisplatin‐based chemotherapy with external beam radiotherapy and brachytherapy. Cervical cancer causes more than one quarter of a million deaths per year as a result of grossly deficient treatments in many developing countries. This warrants a concerted global effort to counter the shocking loss of life and suffering that largely goes unreported. This article provides a review of the biology, prevention, and treatment of cervical cancer, and discusses the global cervical cancer crisis and efforts to improve the prevention and treatment of the disease in underdeveloped countries. Cancer 2017;123:2404–12. © 2017 American Cancer Society .