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Antiangiogenic agents in head and neck squamous cell carcinoma: Tired of going solo
Author(s) -
Chau Nicole G.,
Haddad Robert I.
Publication year - 2016
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.30352
Subject(s) - medicine , head and neck , basal cell , head and neck squamous cell carcinoma , radiation therapy , oncology , head and neck cancer , surgery
Antiangiogenic therapies as single agents have failed to demonstrate significant antitumor activity in heavily pretreated, unselected populations with recurrent/metastatic head and neck squamous cell carcinoma. Much work is needed to evaluate rational strategies for combining antiangiogenic agents with other systemic therapies or with radiotherapy for head and neck squamous cell carcinoma to move the field forward. See also pages 3641‐9.