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Human papillomavirus detection in a “Digital” age
Author(s) -
Bishop Justin A.,
Ha Patrick K.
Publication year - 2016
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.29979
Subject(s) - medicine , human papillomavirus , polymerase chain reaction , oncology , basal cell , identification (biology) , digital polymerase chain reaction , risk stratification , computational biology , gene , biology , genetics , botany
It is increasingly important to identify the presence of human papillomavirus (HPV) in patients with oropharyngeal squamous cell carcinoma, because HPV status is now useful for clinical trial stratification, prognostic determination, diagnosis in patients with neck masses, and identification of the primary tumor site. Therefore, it is important that the technique used for identification be feasible, accurate, reproducible, and cost effective. The authors summarize these aspects of HPV detection and the use of newer digital polymerase chain reaction technology for this purpose. See also pages.