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Genetic variants and response to cancer treatments
Author(s) -
Warusavitarne Janindra,
Stebbing Justin,
Faiz Omar
Publication year - 2015
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.29257
Subject(s) - medicine , single nucleotide polymorphism , drug response , genetics , gene , genetic variants , cancer , bioinformatics , drug development , drug , oncology , computational biology , pharmacology , genotype , biology
The authors discuss new findings that single nucleotide polymorphisms in genes associated with off‐target effects of antiangiogenesis agents have a bearing on clinical outcomes. This, in turn, reveals potential new targets for drug development.