Premium
Integration of cancer genomics with treatment selection
Author(s) -
Ow Thomas J.,
Sandulache Vlad C.,
Skinner Heath D.,
Myers Jeffrey N.
Publication year - 2013
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.28304
Subject(s) - medicine , genomics , cancer , selection (genetic algorithm) , computational biology , genome , genetics , artificial intelligence , biology , gene , computer science
The field of cancer genomics is rapidly advancing as new technology provides detailed genetic and epigenetic profiling of human cancers. The amount of new data available describing the genetic make‐up of tumors is paralleled by rapid advances in drug discovery and molecular therapy currently under investigation to treat these diseases. This review summarizes the challenges and approaches associated with the integration of genomic data into the development of new biomarkers in the management of cancer. Cancer 2013 ;119:3914–3928. © 2013 American Cancer Society .