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Intra‐arterial chemotherapy for head and neck cancer
Author(s) -
Robbins K. Thomas,
Howell Stephen B.,
Williams James Scott
Publication year - 2010
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.24930
Subject(s) - medicine , cisplatin , head and neck cancer , head and neck , chemotherapy , significant difference , chemoradiotherapy , anesthesia , surgery , cancer
Although it would appear that there is no difference in outcomes for intra‐arterial (IA) versus intravenous cisplatin chemoradiotherapy, one must consider the technique by which the tumors were infused. The authors used the less effective method of bilateral infusion in 58% of patients compared to <5% by us. This large difference could have affected the outcome thus leaving the value of IA cisplatin infusion in question.