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Genetic stratification of Wilms tumor
Author(s) -
Geller James I.
Publication year - 2008
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.23673
Subject(s) - wilms' tumor , genotype , phenotype , medicine , wilms tumour , cancer , genetics , gene , evolutionary biology , biology
Subsequent to the initial indentification of the Wilms tumor‐supressor gene ( WT1 ) two decades ago, novel insights pertaining to the molecular and genetic heterogenous nature of Wilms tumor have reshaped our understanding of this cancer. Additional genotype‐phenotype correlations are beginning to emerge, raising new questions about how to best evaluate and treat affected children.