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Soft tissue sarcomas of the skull base: Time for a new paradigm
Author(s) -
DeMonte Franco
Publication year - 2007
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.22883
Subject(s) - medicine , skull , soft tissue , sarcoma , head and neck , radiation therapy , surgery , resection , head and neck cancer , soft tissue sarcoma , pathology
Wide surgical resection with negative margins remains the treatment of choice for soft tissue sarcomas of the head and neck and skull base. There is Level 1 evidence to support the addition of radiation to surgical resection for extremity soft tissue sarcoma, but its use in head and neck and skull base tumors is less well established, although it probably is worthwhile. The role of traditional chemotherapy, if any, probably is small, and newer agents need to be assessed under controlled conditions to identify benefit.