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Current status of lymph node‐positive prostate cancer
Author(s) -
Swanson Gregory P.,
Thompson Ian M.,
Basler Joseph
Publication year - 2006
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.22034
Subject(s) - medicine , prostate cancer , lymph node , oncology , cancer
In early surgical series, the incidence of positive lymph nodes in patients with prostate cancer was approximately 40%. In the modern era of screening and improved patient selection, the incidence is now <10%, although most series excluded patients with higher risk disease. The risk of having positive lymph nodes is influenced by disease stage, prostate‐specific antigen level, and tumor grade and by the aggressiveness of lymph node dissection. Many of the same factors predict the outcome of these patients. Although the percentage of patients with positive lymph nodes has declined, there remain significant numbers of patients with lymph node‐positive prostate cancer, and it remains a therapeutic dilemma. Cancer 2006. © 2006 American Cancer Society.