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Epidermal growth factor receptor‐targeted treatment for advanced colorectal carcinoma
Author(s) -
Venook Alan P.
Publication year - 2005
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.21123
Subject(s) - colorectal cancer , medicine , epidermal growth factor receptor , pathogenesis , cancer research , targeted therapy , epidermal growth factor , oncology , carcinoma , cancer , receptor
Substantial effort has focused on the development of novel targeted agents for treating patients with late‐stage colorectal carcinoma. These agents are designed specifically to inhibit biochemical processes associated with pathogenesis. Numerous molecules targeting the epidermal growth factor receptor have been investigated as therapeutic agents and appear to herald a shift in the treatment paradigm for colorectal carcinoma. Cancer 2005. © 2005 American Cancer Society.