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Is c‐kit (CD117) immunolocalization in cell block preparations useful in the differentiation of adenoid cystic carcinoma from pleomorphic adenoma?
Author(s) -
Chandan Vishal S.,
Wilbur David,
Faquin William C.,
Khurana Kamal K.
Publication year - 2004
Publication title -
cancer cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.20301
Subject(s) - adenoid cystic carcinoma , pleomorphic adenoma , adenoid , medicine , pathology , cd117 , adenoma , carcinoma , salivary gland , biology , stem cell , cd34 , genetics
The authors examined the role of c‐kit antigen expression in cell block material obtained by fine‐needle aspiration in differentiating between adenoid cystic carcinoma and pleomorphic adenoma. It was found that c‐kit expression was not restricted to adenoid cystic carcinomas; instead, c‐kit was expressed in pleomorphic adenomas as well. Thus, c‐kit was not useful in distinguishing between these two types of lesions.