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Wilm's Tumor: An Update
Author(s) -
D'ANGIO G. J.,
BECKWITH J. B.,
BRESLOW N. E.,
BISHOP H. C.,
EVANS A. E.,
FAREWELL V.,
FERNBACH D.,
GOODWIN W. E.,
JONES B.,
LEAPE L. L.,
PALMER N. F.,
TEFFT M.,
WOLFF J. A.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.1980.45.s7.1791
Subject(s) - medicine , radiation therapy , stage (stratigraphy) , wilms' tumor , disease , survival rate , intensive care medicine , oncology , surgery , paleontology , biology
Major advances have been made against Wilms' tumor as a result of treatment methods developed by single institutions that then have been confirmed and extended by national cooperating groups. Better survival rates have been achieved, and therapy has been refined so that treatment can be reduced in early stage disease without jeopardizing tumor control. This results in fewer short‐ and long‐term complications, an especially important consideration in children. Their organs and tissues are vulnerable to anti‐mitotic treatments such as chemo‐ and radiotherapy, that can produce disabling if not lethal dysfunctions. This progress has been the result of the cooperative efforts by multiple specialists, and provides evidence of the value of such integrated studies. They have changed the outlook from a 90% death rate in the early years of this century to the 90% survival rate now possible with modern management.