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BRCA ‐related ovarian carcinoma
Author(s) -
Rubin Stephen C.
Publication year - 2003
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.11341
Subject(s) - medicine , ovarian carcinoma , ovarian cancer , oncology , brca mutation , carcinoma , clinical trial , gynecology , ovarian carcinomas , cancer
The author comments on a report in this issue of Cancer by investigators who used clinical response endpoints and chemoresistance testing to confirm the improved survival of women with hereditary ovarian carcinoma compared with women who had sporadic ovarian carcinoma. The possible use of BRCA mutation status to improve patient care, the future of translational research, and the difficulties in proceeding with large‐scale prospective trials are among the topics discussed. See also pages 2187–95.