Open AccessBlood oxygenation level dependent functional magnetic resonance imaging
Author(s) -
Mcintyre Michael,
Richter Wolfgang,
Morden Dara,
Wennerberg Anders,
Frankenstein Uta
Publication year - 2003
Publication title -
concepts in magnetic resonance part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.229
H-Index - 49
eISSN - 1552-5023
pISSN - 1546-6086
DOI - 10.1002/cmr.a.10049
Subject(s) - functional magnetic resonance imaging , dephasing , blood oxygenation , functional magnetic resonance spectroscopy of the brain , magnetic resonance imaging , nuclear magnetic resonance , relaxation (psychology) , signal (programming language) , chemistry , neuroscience , physics , computer science , psychology , medicine , radiology , programming language , quantum mechanics
The objective of the present article is to provide an introduction to the most widely used method of imaging the functional neuroanatomy of the human brain. The inferential relationship between neural activation and a magnetic resonance signal change is described in detail. The contrast between an active state and a baseline depends on an increased ratio of oxyhemoglobin to deoxyhemoglobin, a longer transverse relaxation time ( T * 2 ), decreased levels of paramagnetically induced dephasing, and a consequently stronger signal in the active state. Issues pertaining to image interpretation, spatial and temporal resolution, and image stability are described. © 2003 Wiley Periodicals, Inc. Concepts Magn Reson 16A: 5–15, 2003