Open AccessOptical probes and the applications in multimodality imaging
Author(s) -
Liu Yang,
Yu Gang,
Tian Mei,
Zhang Hong
Publication year - 2011
Publication title -
contrast media & molecular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.714
H-Index - 50
eISSN - 1555-4317
pISSN - 1555-4309
DOI - 10.1002/cmmi.428
Subject(s) - multimodality , modality (human–computer interaction) , optical imaging , modalities , molecular imaging , preclinical imaging , medical imaging , bioluminescence imaging , computer science , fluorescence lifetime imaging microscopy , visualization , medical physics , in vivo , medicine , artificial intelligence , fluorescence , chemistry , optics , physics , luciferase , biology , social science , transfection , biochemistry , microbiology and biotechnology , sociology , world wide web , gene
Abstract Optical imaging essentially refers to in vivo fluorescence imaging and bioluminescence imaging. These types of imaging are widely used visualization methods in biomedical research and are important in molecular imaging. A new generation of imaging agents called multimodal probes have emerged in the past few years. These probes can be detected by two or more imaging modalities, which harnesses the strengths of the different modalities and enables researchers to obtain more information than can be achieved using only one modality. Owing to its low cost and the large number of probes available, the optical method plays an important role in multimodality imaging. In this mini‐review, we describe the available multimodal imaging probes for in vivo imaging that combine optical imaging with other modalities. Copyright © 2011 John Wiley & Sons, Ltd.