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Cover Feature: Broad‐Spectrum Antifungal Agents: Fluorinated Aryl‐ and Heteroaryl‐Substituted Hydrazones (ChemMedChem 1/2021)
Author(s) -
Thamban Chandrika Nishad,
Dennis Emily K.,
Brubaker Katelyn R.,
Kwiatkowski Stefan,
Watt David S.,
GarneauTsodikova Sylvie
Publication year - 2021
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.202000958
Subject(s) - antifungal , broad spectrum , cover (algebra) , combinatorial chemistry , aryl , chemistry , feature (linguistics) , antifungal drug , stereochemistry , organic chemistry , biology , microbiology and biotechnology , engineering , mechanical engineering , linguistics , alkyl , philosophy
The Cover Feature shows a fluorinated aryl substituted monohydrazone attacking a field of diverse drug‐resistant pathogenic fungi, which are responsible for substantial damage to the health of immunocompromised patients. In various biological assays, this compound and its analogues exhibited exceptional promise as novel antifungal agents. More information can be found in the Full Paper by David S. Watt, Sylvie Garneau‐Tsodikova et al. Cover design by Dr. Nishad Thamban Chandrika and Dr. Sylvie Garneau‐Tsodikova.