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Front Cover: Dopamine‐Modified Zero‐Valent Iron Nanoparticles for Dual‐Modality Photothermal and Photodynamic Breast Cancer Therapy (ChemMedChem 17/2020)
Author(s) -
Yu Hsin Her,
Lin ChiaHua,
Chen YiChun,
Chen HungHsiang,
Lin YuJing,
Lin KunYi Andrew
Publication year - 2020
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.202000602
Subject(s) - photothermal therapy , photodynamic therapy , reactive oxygen species , zerovalent iron , chemistry , breast cancer , cancer , nanoparticle , cancer research , photothermal effect , cancer cell , biophysics , nanotechnology , materials science , medicine , biochemistry , biology , organic chemistry , adsorption
The Front Cover shows the polydopamine (PDA)‐modified nano zero‐valent iron (nZVI@PDA) offering high light‐to‐heat conversion and reactive oxygen species (ROS) generation efficiency under near‐infrared irradiation, thus leading to a phototherapeutic effect against human breast cancer cells without side effects. The results also demonstrated that nZVI@PDA induced apoptosis in MCF‐7 cells, suggesting that phototherapy induced by nZVI@PDA leads to irreversible damage of breast cancer cells. This study provides a facile method to develop an efficacious dual‐modality nZVI@PDA for phototherapeutic treatment of breast cancer. More information can be found in the Full Paper by Chia‐Hua Lin, Kun‐Yi Andrew Lin et al.