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Cover Feature: Further Investigations into Rigidity‐Activity Relationships in BisQAC Amphiphilic Antiseptics (ChemMedChem 8/2020)
Author(s) -
Leitgeb Austin J.,
Feliciano Javier A.,
Sanchez Hugo A.,
Allen Ryan A.,
Morrison Kelly R.,
Sommers Kyle J.,
Carden Robert G.,
Wuest William M.,
Minbiole Kevin P. C.
Publication year - 2020
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.202000182
Subject(s) - amphiphile , disinfectant , rigidity (electromagnetism) , cover (algebra) , chemistry , nanotechnology , combinatorial chemistry , computational biology , stereochemistry , biology , materials science , organic chemistry , engineering , copolymer , mechanical engineering , composite material , polymer
The Cover Feature shows the application of a disinfectant on a surface in a hospital setting, while a child plays nearby. The development of novel disinfectants is crucial to inhibiting the transmission of human pathogens in a variety of locations. Wuest, Minbiole, and coworkers are working to develop a better understanding of how novel multicationic quaternary ammonium compounds (QACs) might best eradicate a variety of bacteria, including those exhibiting resistance. The effects of structural rigidity of the biscationic QAC compounds is investigated. Original illustration by Orlena Roe. More information can be found in the Communication by Austin J. Leitgeb, William M. Wuest, Kevin P. C. Minbiole et al..