Premium
Front Cover: Axially Chiral Cannabinols: A New Platform for Cannabinoid‐Inspired Drug Discovery (ChemMedChem 9/2020)
Author(s) -
Navaratne Primali V.,
Wilkerson Jenny L.,
Ranasinghe Kavindri D.,
Semenova Evgeniya,
Felix Jasmine S.,
Ghiviriga Ion,
Roitberg Adrian,
McMahon Lance R.,
Grenning Alexander J.
Publication year - 2020
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.202000140
Subject(s) - front cover , cannabinoid , drug discovery , chemistry , cover (algebra) , nanotechnology , materials science , engineering , biochemistry , receptor , mechanical engineering
The Front Cover is a representation of an axially‐chiral‐cannabinoid ( ax‐CBNs) , a new cannabinoid family that is conceptualized, synthesized, and evaluated in this issue of ChemMedChem . The authors have hypothesized that cannabinoids with restricted rotation and biased three‐dimensional conformations may be attractive new leads for drug discovery. The drawing shows the biaryls about the cannabinoid scaffold in an orthogonal alignment, and the pathway leads from phytocannabinoids to the newly developed ax‐CBNs . More information can be found in the Communication by Alexander J. Grenning.