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Front Cover: A Smart Nanotherapeutic Agent for in vitro and in vivo Reversal of Heavy‐Metal‐Induced Causality: Key Information from Optical Spectroscopy (ChemMedChem 5/2020)
Author(s) -
Adhikari Aniruddha,
Biswas Pritam,
Mondal Susmita,
Das Monojit,
Darbar Soumendra,
Hameed Ahmed M.,
Alharbi Ahmed,
Ahmed Saleh A.,
Sankar Bhattacharya Siddhartha,
Pal Debasish,
Kumar Pal Samir
Publication year - 2020
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.202000098
Subject(s) - nanomedicine , chelation , chemistry , nanotechnology , front cover , in vivo , nanoparticle , combinatorial chemistry , biophysics , environmental chemistry , cover (algebra) , materials science , organic chemistry , engineering , biology , microbiology and biotechnology , mechanical engineering
The Front Cover shows the efficacy of a nanohybrid containing covalently attached citrate functionalized Mn 3 O 4 nanoparticles (nanomedicine) for remediation of heavy metal toxicity due to environmental pollution and reckless lifestyle. The nanomedicine chelates the heavy metal and removes it from the body, simultaneously scavenging the oxidative stress generated by the toxicity. While a detailed in vitro spectroscopic study for the heavy metal chelation and ROS scavenging reveals microscopic understanding, a comprehensive in vivo experiment on mice models confirms the efficacy of the nanomedicine in animals. (Featured illustration by Aniruddha Adhikari.) More information can be found in the Full Paper by Samir Kumar Pal et al. on page 420 in Issue 5, 2020 (DOI: 10.1002/cmdc.201900543).