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Front Cover: Synthesis and Study of Multifunctional Cyclodextrin–Deferasirox Hybrids (ChemMedChem 16/2019)
Author(s) -
Gascon Jose Miguel,
Oliveri Valentina,
McGown Andrew,
Kaya Ecem,
Chen YuLin,
Austin Carol,
Walker Martin,
Platt Frances M.,
Vecchio Graziella,
Spencer John
Publication year - 2019
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201900454
Subject(s) - deferasirox , cyclodextrin , cover (algebra) , front cover , front (military) , front and back ends , chemistry , nanotechnology , combinatorial chemistry , medicine , computer science , engineering , materials science , biochemistry , operating system , mechanical engineering , thalassemia
The Front Cover depicts two horses (taken by the lead author J.S.) that look like they are “joined at the hips.” Although they look “connected,” each horse here has its own unique capabilities and character. As the saying goes, “two heads are better than one.” Similarly, in this paper, our group created multifunctional hybrids of cyclodextrin and deferasirox, with each component contributing to improved therapy for lipid and metal dyshomeostasis management in Niemann Pick C disease. More information can be found in the Full Paper by John Spencer et al. on page 1484 in Issue 16, 2019 (DOI: 10.1002/cmdc.201900334).