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Front Cover: Synthesis and Anticancer Evaluation of 1,4‐Naphthoquinone Derivatives Containing a Phenylaminosulfanyl Moiety (ChemMedChem 5/2019)
Author(s) -
Ravichandiran Palanisamy,
Subramaniyan Sivakumar Allur,
Kim SeonYoung,
Kim JongSoo,
Park ByungHyun,
Shim Kwan Seob,
Yoo Dong Jin
Publication year - 2019
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201900099
Subject(s) - front cover , moiety , anticancer drug , combinatorial chemistry , naphthoquinone , chemistry , cancer , stereochemistry , cover (algebra) , cancer cell , pharmacology , drug , biology , medicine , organic chemistry , engineering , mechanical engineering
The Front Cover illustrates the capability of naphthoquinones to make the hybrid conjugation with cancer cells at nanomolar concentrations. Various types of cancer can be highly lethal, and recent research discloses that every year there are an estimated 8.2 million cancer deaths worldwide. The drug design and experimental results of this study clearly reveal that naphthoquinone derivatives could be potent anticancer agents against a number of cancer types. More information can be found in the Full Paper by Dong Jin Yoo et al. on page 532 in Issue 5, 2019 (DOI: 10.1002/cmdc.201800749).