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Recent Advances in Functional‐Polymer‐Decorated Transition‐Metal Nanomaterials for Bioimaging and Cancer Therapy
Author(s) -
Zhao Wei,
Li Aihua,
Zhang Aitang,
Zheng Yiwei,
Liu Jingquan
Publication year - 2018
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201800462
Subject(s) - nanomaterials , photothermal therapy , materials science , nanotechnology , biocompatibility , cancer therapy , polymer , photodynamic therapy , cancer imaging , radiation therapy , nanomedicine , cancer , nanoparticle , chemistry , medicine , radiology , organic chemistry , metallurgy , composite material
In this review, we focus on recent advances in the synthesis of polymer‐functionalized transition‐metal‐based nanomaterials and follow this up by discussing their applications in bioimaging diagnosis and cancer therapy. Transition‐metal‐based nanomaterials show great potential in cancer therapy owing to their intensive near‐IR absorption, excellent photothermal conversion efficiency, strong X‐ray attenuation, and magnetic properties. Functional polymers are usually introduced by a one‐step or multistep method to further endow these nanomaterials with great biocompatibility and physiological stability. Polymer‐decorated transition‐metal nanomaterials show great potential in multimodal imaging diagnosis (photoacoustic imaging, computed tomography, photoluminescence imaging, positron emission tomography, etc.) and cancer therapy (chemotherapy, photothermal therapy, microwave therapy, radiotherapy, photodynamic therapy). At the end of this review, the prospects of these polymer‐decorated transition‐metal‐based nanomaterials are also discussed.