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Front Cover: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity (ChemMedChem 9/2018)
Author(s) -
Coghi Paolo,
Yaremenko Ivan A.,
Prommana Parichat,
Radulov Peter S.,
Syroeshkin Mikhail A.,
Wu Yu Jun,
Gao Jia Ying,
Gordillo Floria M.,
Mok Simon,
Wong Vincent Kam Wai,
Uthaipibull Chairat,
Terent'ev Alexander O.
Publication year - 2018
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201800268
Subject(s) - front cover , cover (algebra) , chemistry , drug discovery , combinatorial chemistry , biochemistry , engineering , mechanical engineering
The Front Cover shows the effort of three collaborators from Thailand ( B IOTEC), Macau ( M UST), and Russia ( Z elinsky Institute) on the discovery of novel anticancer and antimalarial compounds. The present findings showed for the first time promising new peroxide derivatives with much higher anticancer activity than the counterpart antimalarial activity, and with considerable increase of selectivity. The study also provides a unique synthetic approach to yield new classes of structurally modified peroxides for both anticancer and antimalarial treatment. Cover illustration by Lo Hang Hong, MUST. More information can be found in the Full Paper by Vincent Kam Wai Wong, Chairat Uthaipibull, Alexander O. Terent′ev et al. on page 902 in Issue 9, 2018 (DOI: 10.1002/cmdc.201700804).