Premium
Multitarget Drug Discovery and Polypharmacology
Author(s) -
Bolognesi Maria Laura,
Cavalli Andrea
Publication year - 2016
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201600161
Subject(s) - drug discovery , drug repositioning , drug , computer science , pharmacology , medicine , bioinformatics , biology
Promising promiscuity : Guest editors Maria Laura Bolognesi and Andrea Cavalli set the stage for this ChemMedChem Special Issue on Polypharmacology and Multitarget Drugs. They highlight cases in which a departure from the “one target, one drug” paradigm has proven advantageous, with single molecules that can engage two or more targets to address a given pathology. Articles in this issue underscore the importance of focusing ever more attention to polypharmacology in drug discovery efforts.