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Inside Cover: Directed Modulation of Protein Kinase C Isozyme Selectivity with Bisubstrate‐Based Inhibitors (ChemMedChem 12/2012)
Author(s) -
van Wandelen Loek T. M.,
van Ameijde Jeroen,
Mady Ahmed S. A.,
Wammes Angelique E. M.,
Bode Alois,
Poot Alex J.,
Ruijtenbeek Rob,
Liskamp Rob M. J.
Publication year - 2012
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201290060
Subject(s) - selectivity , isozyme , cover (algebra) , chemistry , peptide , enzyme , combinatorial chemistry , protein kinase a , kinase , biochemistry , catalysis , mechanical engineering , engineering
The inside cover picture shows real‐time peptide microarrays being used to discover selective peptides that are connected to a set of ATP analogues yielding bisubstrate‐based inhibitors displaying tuneable selectivity amongst protein kinase C isozymes. For more details, see the Full Paper by Rob M. J. Liskamp et al. on p. 2113 ff.