Premium
A Monoreactive Bifunctional Triazacyclononane Phosphinate Chelator with High Selectivity for Gallium‐68
Author(s) -
Šimeček Jakub,
Zemek Ondřej,
Hermann Petr,
Wester HansJürgen,
Notni Johannes
Publication year - 2012
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201200261
Subject(s) - phosphinate , bifunctional , chelation , gallium , selectivity , combinatorial chemistry , chemistry , computer science , biochemistry , organic chemistry , fire retardant , catalysis
Gallium‐68 preferred: The macrocyclic phosphinate chelator NOPO exhibits pronounced affinity and selectivity for the Ga 3+ ion, rendering it highly useful for applications in 68 Ga radiopharmaceuticals for positron emission tomography.