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Inside Cover: Cell‐Free HIV‐1 Virucidal Action by Modified Peptide Triazole Inhibitors of Env gp120 (ChemMedChem 8/2011)
Author(s) -
Bastian Arangassery R.,
McFadden Karyn,
Duffy Caitlin,
Rajagopal Srivats,
Contarino Mark R.,
Papazoglou Elisabeth,
Chaiken Irwin
Publication year - 2011
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201190033
Subject(s) - peptide , human immunodeficiency virus (hiv) , triazole , cover (algebra) , virus , chemistry , click chemistry , cell , oligopeptide , virology , stereochemistry , combinatorial chemistry , biochemistry , biology , mechanical engineering , organic chemistry , engineering
The inside cover picture shows the encounter of HIV‐1 (grey) with a peptide triazole inhibitor (green) of viral Env gp120 (blue). This encounter leads to blockade of host‐cell infection by the virus and can cause cell‐independent virus rupture. HIV‐1 is depicted interacting with peptide triazole inhibitor displayed multivalently on gold nanoparticles (yellow). Illustration designed by Andrew Holmes (Drexel University, USA). For more details, see the Communication by Irwin Chaiken et al. on p. 1335 ff.