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Identification and Characterization of Inhibitors of the Aminoglycoside Resistance Acetyltransferase Eis from Mycobacterium tuberculosis
Author(s) -
Green Keith D.,
Chen Wenjing,
GarneauTsodikova Sylvie
Publication year - 2012
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201100332
Subject(s) - library science , computer science
Stopping resistance in tuberculosis: The unusually regioversatile acetyltransferase Eis is a cause of resistance to kanamycin A in cases of tuberculosis. En route to new tuberculosis treatments, several inhibitors of the Eis enzyme were identified and characterized.

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