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Electrocyclization‐Based Labeling Allows Efficient In Vivo Imaging of Cellular Trafficking
Author(s) -
Tanaka Katsunori,
Minami Kaori,
Tahara Tsuyoshi,
Fujii Yohei,
Siwu Eric R. O.,
Nozaki Satoshi,
Onoe Hirotaka,
Yokoi Satomi,
Koyama Koichi,
Watanabe Yasuyoshi,
Fukase Koichi
Publication year - 2010
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.201000027
Subject(s) - computer science , in vivo , fluorescence , chemistry , computational biology , high content screening , live cell imaging , nanotechnology , information retrieval , cell , biology , biochemistry , materials science , physics , microbiology and biotechnology , quantum mechanics
Labeling the living! New synthetic chemistry allows living cells to be labeled for 10 min at extremely low concentrations without deactivating cell functions; lymphocyte trafficking was visualized with high‐contrast fluorescence imaging at the whole‐body level.