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Asborin: The Carbaborane Analogue of Aspirin
Author(s) -
Scholz Matthias,
Bensdorf Kerstin,
Gust Ronald,
HeyHawkins Evamarie
Publication year - 2009
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.200900072
Subject(s) - aspirin , cyclooxygenase , yield (engineering) , chemistry , medicine , pharmacology , materials science , biochemistry , enzyme , metallurgy
Asborin , the carbaborane analogue of aspirin, was obtained by a high‐yield synthetic procedure and proved to be an active cyclooxygenase (COX) inhibitor (H: white, B: beige, C: gray, O: blue).