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Molecular Approaches towards the Inhibition of the Signal Transducer and Activator of Transcription 3 (Stat3) Protein
Author(s) -
Fletcher Steven,
Turkson James,
Gunning Patrick T.
Publication year - 2008
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.200800123
Subject(s) - library science , citation , chemistry , computer science
Molecular approaches towards Stat3 inhibition : Stat3 inhibition represents an exciting new approach to the treatment of cancer. The advances in the direct molecular inhibition of Stat3 are highlighted through discussion of the various inhibitors currently under investigation, including peptide sequences, peptidomimetics, small molecules and platinum‐based agents.