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Cover Picture: A glucose derivative as natural alternative to the cyclohexane‐1,2‐diamine ligand in the anticancer drug oxaliplatin? (ChemMedChem 4/2007)
Author(s) -
Berger Isabella,
Nazarov Alexey A.,
Hartinger Christian G.,
Groessl Michael,
Valiahdi SeiedM.,
Jakupec Michael A.,
Keppler Bernhard K.
Publication year - 2007
Publication title -
chemmedchem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.200790008
Subject(s) - oxaliplatin , chemistry , diamine , platinum , anticancer drug , ligand (biochemistry) , moiety , combinatorial chemistry , stereochemistry , drug , organic chemistry , pharmacology , biochemistry , medicine , cancer , receptor , colorectal cancer , catalysis
The cover picture shows a train charged with sugar driving into a tumor cell, representing the concept of a targeted transfer of a platinum—carbohydrate complex. The coupling of the sugar to the platinum moiety was carried out in the quest for more selective tumor‐inhibting drugs. For details, see the Full Paper by A. A. Nazarov, B. K. Keppler, et al. on p. 505 ff. (LEGO® DUPLO® train used with special permission. ©2007 The LEGO Group.)