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Sequence‐Based Identification of Specific Drug Target Regions in the Thymidylate Synthase Enzyme Family
Author(s) -
Ferrari Stefania,
Losasso Valeria,
Costi Maria Paola
Publication year - 2008
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.200700215
Subject(s) - thymidylate synthase , biology , computational biology , sequence (biology) , identification (biology) , enzyme , sequence analysis , biochemistry , genetics , gene , cancer , fluorouracil , botany
Thymidylate synthases from pathogenic organisms : Sequence analysis and knowledge‐based grouping have provided a step forward in the identification of potential drug target regions in thymidylate synthases. This provides a unique approach toward blocking the growth of pathogenic organisms.