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microRNA: an Emerging Therapeutic
Author(s) -
Scaria Vinod,
Hariharan Manoj,
Brahmachari Samir K.,
Maiti Souvik,
Pillai Beena
Publication year - 2007
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.200600278
Subject(s) - microrna , biology , computational biology , mechanism (biology) , carcinogenesis , genetics , gene , philosophy , epistemology
microRNAs are a recently discovered class of small noncoding RNAs which have been shown to regulate critical biological processes in higher eukaryotes. The regulatory impacts of microRNAs are now shown to encompass biological processes ranging from growth and development to oncogenesis and host–pathogen interaction. In this paper, we highlight the opportunities in developing novel diagnostics and therapeutics based on the microRNA regulatory mechanism.