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Platensimycin, a New Antibiotic and “Superbug Challenger” from Nature
Author(s) -
Häbich Dieter,
von Nussbaum Franz
Publication year - 2006
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.200600145
Subject(s) - antibiotics , biology , computational biology , microbiology and biotechnology
Natural products have once again proven their value as guideposts for unexplored targets. “Old‐fashioned” extract screening integrated into an innovative assay set‐up has opened a new playground for medicinal chemists. Platensimycin is the first member of a novel class of antibiotics that acts through a clinically unexploited target.