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Trapping Norovirus by Glycosylated Hydrogels: a Potential Oral Antiviral Drug
Author(s) -
Zhang Yalong,
Yao Qingjia,
Xia Chengfeng,
Jiang Xi,
Wang Peng George
Publication year - 2006
Publication title -
chemmedchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.817
H-Index - 100
eISSN - 1860-7187
pISSN - 1860-7179
DOI - 10.1002/cmdc.200600135
Subject(s) - norovirus , clearance , self healing hydrogels , virology , murine norovirus , drug , virus , drug delivery , antiviral drug , outbreak , chemistry , microbiology and biotechnology , medicine , biology , pharmacology , organic chemistry , urology
Trapped! Hydrogels have potential for use as prophylactic drugs against norovirus infection, as they absorb virus particles with high affinity. Virus entrapped in the hydrogel would be rendered harmless as it is cleared from the body. This approach could be useful in the worldwide fight against viral gastroenteritis outbreaks.